Predicting Recurrence and Progession of Non Muscle Invasive Urothelial Cell Carcinoma of Bladder by Clinical and Pathological Prognostic Factors

, Se Young Choi; , In Ho Chang

Review Article

The Korean Journal of Urological Oncology 2015;13(1):1-10.
Published online April 30, 2015.

비근침윤성 방광암의 재발과 진행을 예측하는 임상, 병리적 예후 인자

최세영, 장인호

중앙대학교 의과대학 비뇨기과학교실

Predicting Recurrence and Progession of Non Muscle Invasive Urothelial Cell Carcinoma of Bladder by Clinical and Pathological Prognostic Factors

Se Young Choi , In Ho Chang

Department of Urology, College of Medicine, Chung-Ang University, Seoul, Korea

Correspondence: In Ho Chang

Abstract

About 80% of Bladder cancer is non muscle invasive bladder cancer (NMIBC). Despite of appropriate therapy, a lot of NMIBC recur as a superficial tumor or progress to muscle invasive disease. Several studies about prognostic factors of recurrence and progression have reported a single risk factor variously according to each study. These efforts were developed to predict the risk by scoring system and large-scale studies had been conducted. These studies had limitations that their patients did not receive BCG (bacillus Calmette-Guerin) immunotherapy, immediate intravesical chemotherapy, second-look TUR (transurethral resection) in high-risk group. Through studies to date, patients with NMIBC have showed heterogenous prognosis and a more sophisticated scoring system can give personalized treatment and exact prediction. (Korean J Urol Oncol 2015;13:1-10)

Key Words: Urinary bladder neoplasms, Risk factors, Prognosis, Scoring method