The Korean Journal of Urological Oncology 2014;12(1):10-15.
Published online April 30, 2014.
하대정맥 혈전을 동반한 신세포암의 치료
권택민, 홍준혁
울산대학교 의과대학 서울아산병원 비뇨기과
Treatment of Renal Cell Carcinoma with Inferior Vena Cava Thrombu
Taekmin Kwon , Jun Hyuk Hong
Department of Urology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
Correspondence:  Jun Hyuk Hong
Abstract
The prognosis for patients with renal cell carcinoma (RCC) with inferior vena cava (IVC) thrombus is very poor due to the absence of effective chemotherapeutic agents and the limited usefulness of radiation therapy in this setting. Surgery provided the only hope of a cure in these patients, although resection of RCC with IVC thrombus is technically demanding and is associated with high perioperative morbidity and mortality rates. For this reason, an aggressive approach has been established as the mainstay of treatment. Recent advances in the understanding of the biology of intravascular tumor invasion and the considerable progress in the fields of diagnosis and treatment of this entity, with innovative surgical and systemic strategies, have completely redefined the management of these patients. Basically, treatment must be individualized to every patient based on tumor biology and patient performance status. Additionally, the decision to perform invasive surgery in these patients should be done with caution. (Korean J Urol Oncol 2014;12:10-15)
Key Words: Carcinoma, Renal cell, Thrombosis, Vena cava, Inferior


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