국소 전립선암에서 예측 모형으로서의 전립선특이항원속도의 역할 |
함원식 |
연세대학교 의과대학 비뇨기과학교실, 비뇨의과학연구소 |
Prostate-Specific Antigen Velocity as a Prognostic Tool in Localized Prostate Cancer |
Won Sik Ham |
Department of Urology and Urological Science Institute, Yonsei University College of Medicine, Seoul, Korea |
Correspondence:
Won Sik Ham |
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Abstract |
It has been reported that prostate-specific antigen (PSA) velocity (PSAV) is statistically associated with many prostate cancer outcomes, including those related to early detection. However, the clinical use of a marker should depend on clinical and statistical significance. Before PSAV is used to inform decisions such as whether to perform a biopsy, evidence should be clear that doing so would improve clinical outcome. Therefore, the use of PSAV as a marker in localized prostate cancer has sometimes been described as controversial. The purpose of this review is to introduce the conflicting opinions on the role of PSAV as a prognostic tool in localized prostate cancer and the usefulness of PSAV in real clinical practice. (Korean J Urol Oncol 2013;11:116-121) |
Key Words:
Prostate cancer, PSA velocity |