The Korean Journal of Urological Oncology 2013;11(3):116-121.
Published online December 30, 2013.
국소 전립선암에서 예측 모형으로서의 전립선특이항원속도의 역할
함원식
연세대학교 의과대학 비뇨기과학교실, 비뇨의과학연구소
Prostate-Specific Antigen Velocity as a Prognostic Tool in Localized Prostate Cancer
Won Sik Ham
Department of Urology and Urological Science Institute, Yonsei University College of Medicine, Seoul, Korea
Correspondence:  Won Sik Ham
Abstract
It has been reported that prostate-specific antigen (PSA) velocity (PSAV) is statistically associated with many prostate cancer outcomes, including those related to early detection. However, the clinical use of a marker should depend on clinical and statistical significance. Before PSAV is used to inform decisions such as whether to perform a biopsy, evidence should be clear that doing so would improve clinical outcome. Therefore, the use of PSAV as a marker in localized prostate cancer has sometimes been described as controversial. The purpose of this review is to introduce the conflicting opinions on the role of PSAV as a prognostic tool in localized prostate cancer and the usefulness of PSAV in real clinical practice. (Korean J Urol Oncol 2013;11:116-121)
Key Words: Prostate cancer, PSA velocity


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