Ureteral Small Cell Carcinoma: A Case Report

, Se Young Choi; , Soon Chul Myung; , Kyung Do Kim; , Tae Jin Lee

Case Report

The Korean Journal of Urological Oncology 2012;10(2):97-100.
Published online August 30, 2012.

Ureteral Small Cell Carcinoma: A Case Report

Se Young Choi , Soon Chul Myung , Kyung Do Kim , Tae Jin Lee

Departments of Urology and

Correspondence: Kyung Do Kim

Abstract

Extrapulmonary small cell carcinoma (SCC) is not a common disease, furthermore ureteral SCC is very rare. Ureteral SCC is fatal, but there are no standard guidelines for ureteral SCC due to the rareness of this disease and a lack of experience of treating it. Herein, we report a case of ureteral SCC. A 77-year-old woman was presented with a right flank pain, and a right nephronureterectomy with bladder cuff excision was performed. A polypoid and whitish tumor which measured 2cm, was detected in the distal ureter. Microscopically, the SCC components had high nuclear/cytoplasmic ratio, scant delicate cytoplasm, nuclear molding, and hyperchromatic chromatin. The immunohistochemical staining was positive for synaptophysin, chromogranin, and neuron specific enolase. Consequently, we diagnosed the patient as having primary ureteral SCC. In abdominopelvis computed tomography of 6 months after surgery, findings of recurrence were detected. However until 9 months after operation she was alive. (Korean J Urol Oncol 2012;10:97-100)

Key Words: Ureter, Small cell carcinoma