비뇨기계 종양 조기검진에서 18F-FDG PET/CT의 임상적 역할 |
안승현, 최승진1, 장인호2, 한준현, 곽경원, 박상욱, 이용택, 하문수, 지병훈2 |
한전의료재단 한일병원 비뇨기과, 1핵의학과, 2중앙대학교 의과대학 비뇨기과학교실 |
The Clinical Roles of 18F-Fluorodeoxyglucose Positron Emission Tomography/Computerized Tomography for Detecting Urologic Malignancy |
Seung Hyun Ahn , Seung Jin Choi 1, In Ho Jang 2, Jun Hyun Han , Kyung Won Kwak , Sang Yuk Park , Yong Taec Lee , Moon Soo Ha2 , Byung Hoon Chi 2 |
0Departments of Urology, Korea 1Departments of Urology, Nuclear Medicine, Hanil General Hospital and
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Correspondence:
Seung Hyun Ahn |
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Abstract |
Purpose We evaluate the detection rate of Fluorine-18-fluorodeoxyglucose positron emission tomography/ computed tomography (18F-FDG PET/CT) for urologic malignancy, and we compared this with the detection rates of other clinical cancers. Materials and Methods: From January 2003 to December 2006, the total number of healthy subjects who underwent 18F-FDG PET/CT was 2,270. The mean subject age was 54.7 (27-68) years and ratio of males to females was 1.3:1. The results of detecting urologic diseases by 18F-FDG PET/CT were compared with the results of detecting other clinical diseases. Results: Out of 2,270 subjects, 102 (4.49%) urologic diseases were detected on 18F-FDG PET/CT. Renal cysts were found in 61 cases (2.69%), renal stone in 39 cases (1.72%), renal cell carcinoma in 1 case (0.04%) and horseshoe kidney in 1 case (0.04%). The detection rates of other clinical diseases, gastrointestinal diseases were found in 347 cases (15.29%), cardiopulmonary diseases in 194 cases (8.55%), thyroid diseases in 213 cases (9.38%), and obstetric and gynecologic diseases in 114 cases (5.02%). Renal cell carcinoma was detected in only one person, whereas thyroid cancer was detected in 19 cases (0.84%), gastrointestinal cancer in 15 cases (0.66%), lung cancer in 14 cases (0.62%) and ovary and cervical cancer in 11 cases (0.48%). Thyroid cancer was most commonly found and detection rate of urologic malignancy was very low on 18F-FDG PET/CT. Conclusions: 18F-FDG PET/CT was not superior to conventional imaging modalities for detecting urologic cancer. 18F-FDG PET/CT may have a clinical role in cancer staging and follow-up after treatment. (Korean J Urol Oncol 2009;7:12-15) |
Key Words:
18F-fluorodeoxyglucose positron emission tomography/computed tomography, Urologic malignancy |
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