Clinical Significance of Lymph Node Dissection in Prostate Cancer

, Jang-ho Yoon; , Dong-il Kang

Review Article

The Korean Journal of Urological Oncology 2008;6(2):53-59.
Published online August 30, 2008.

전립샘암에서 림프절절제술의 중요성

윤장호, 강동일

인제대학교 의과대학 부산백병원 비뇨기과학교실

Clinical Significance of Lymph Node Dissection in Prostate Cancer

Jang-ho Yoon , Dong-il Kang

Department of Urology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea

Correspondence: Dong-il Kang

Abstract

Radical prostatectomy remains the gold standard methods in clinically localized prostate cancer. Lymph node invasion in localized prostate cancer has poor prognosis. The issue concerning pelvic lymphadenectomy in the management of clinically localized prostate cancer is still debated, however. The purpose of this paper is to review the role, extent, effects of pelvic lymphadenectomy in patients with prostate cancer. The literature of pelvic lymph node dissection in prostate cancer was reviewed using a Medline search. If performed, extended pelvic lymphadenectomy has to be done. Possibility of lymph node invasion in low risk patients is very low, pelvic lymphadenectomy can omit. Patients with intermediate or high risk prostate cancer should undergo extended pelvic lymphadenectomy. Accurate N-staging can be determined by extended pelvic lymphadenectomy. (Korean J Urol Oncol 2008;6:53-59)

Key Words: Prostate cancer, Lymph node, Dissection